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KMID : 0381219700020060073
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Journal of RIMSK
1970 Volume.2 No. 6 p.73 ~ p.77
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CONSUMPTION COAGULOPATHY
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Abstract
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In conditions such as generalized Shwartzman phenomenon, infusion of thromboplastinendogenous (tissue tliromboplasiin´ or exogenous (Venoms), fat embolism and Kasabach-h4erritt syndrome there is a hemorrhagic diathesis of acute onset and a clinical picture dominated by severe circulatory collapse.
The pathogenesis of this disorder is poorly understood, and only recently has it become clear that the hemorrhagic tendency is a consequence of the acute activation of the clotting mechanism, which results in the intravascular consumption of plasma clotting factors.
This group of disorders has been referred to as "Consumption Coagulopathy". In this report, the author described the recent knowledges on pathogenesis, laboratory diagnosis and methods of treatment of this dsorder.
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KEYWORD
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